منابع مشابه
Genetic Basis of Dental Disorders: A Review
Deciphering the relative roles of heredity and environmental factors (“nature vs. nurture”) in the pathogenesis of dental caries and diseases of the periodontium has occupied clinical and basic researchers for decades. Success in the endeavor has come more easily in the case of caries; the complex interactions that occur between host-response mechanisms and mutative microbiologic pathogens in p...
متن کاملThe genetic basis of myeloproliferative disorders.
For many decades, myeloproliferative disorders (MPD) were largely neglected orphan diseases. The conceptual work of William Dameshek in 1951 provided the basis for understanding MPD as a continuum of related syndromes, possibly with a common pathogenetic cause. Recognition of the clonal origin of peripheral blood cells in MPD in 1976 and the ability to grow erythroid colonies in vitro in the ab...
متن کاملP43: Neuroanatomical Basis of Anxiety Disorders
Anxiety is an emotion characterized by an unpleasant manner of inner distress, often accompanied by nervous behavior. Anxiety is related to the particular behaviors of fight or flight responses. The amygdala, the insula and anterior cingulate cortex seem to be critical, and all three have been referred to as the fear network .The amygdala which plays a fundamental role in neural network of fear...
متن کاملInm-6: Molecular Genetic Basis of Infertility
Background: Sexual reproduction affords the stands for conserving genetic characteristics and sequentially, genetic inconsistency may influence the capability to imitate. Materials and Methods: Research was conducted by subject in PubMed and other databases. Results: A significant number of genotypes have been related with infertility phenotypes and evaluation of precise genes in humans and mod...
متن کاملDeciphering the genetic basis of speech and language disorders.
A significant number of individuals have unexplained difficulties with acquiring normal speech and language, despite adequate intelligence and environmental stimulation. Although developmental disorders of speech and language are heritable, the genetic basis is likely to involve several, possibly many, different risk factors. Investigations of a unique three-generation family showing monogenic ...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1989
ISSN: 0021-9738
DOI: 10.1172/jci114176